Contact us

China National Pharmaceutical
Group Corporation(SINOPHARM)
Address: No.20 Zhichun
Road, Haidian District, Beijing, China
Postal Code: 100191
Fax: 86-10-62033332


Learn more >>

Sinopharm News

Adverse Drug-Food Medication Interactions-1

Post Time:2008-03-18 [Large Middle Small]admin View:

It is necessary to know how food can affect the medications to prevent the reduction of drug efficacy or even adverse reactions

Cigarettes - any drug: Don’t smoke within 30 minutes of taking any drug. Because nicotine in the cigarette can speed up the drug degradation in the liver which leads to inadequate drug concentration in the blood and diminish the effectiveness of the ingested drug. According to test, if smoking within 30 minutes after taking medication, patient’s plasma concentration will be 1 / 20 of non-smokers’.

Wine, fruit juice ? aspirin: after liquor into the human body it will be oxidized into acetaldehyde, then further oxidized to acetate. Aspirin can prevent oxidation of acetaldehyde into acetic acid, then cause acetaldehyde accumulation in body, which not only aggravates the fever and pain but also causes liver damage. Moreover the juice can lead to gastrorrhagia by increasing the stimulation on gastric mucosa of aspirin.

Tea ? berberine: tea contains about 10% tannin, which can be decomposed into Tannin in the human body. Tannic acid can precipitate alkaloids in berberine and greatly reduce its efficacy. Therefore, don’t take berberine within two hours before and after drinking tea.

Coffee, cola ?Ibuprofen : Ibuprofen has serious irritation on the gastric mucosa. As the caffeine in coffee and coca in cola stimulate gastric acid secretion, they increase the ibuprofen side effects on the gastric mucosa, and even induce stomach bleeding, gastric perforation.

Milk, fruit juice ? antibiotics: don’t intake antibiotics within 2 hours before and after drinking milk or juice. Milk can cause the medication to work less effectively by reducing the antibiotics activity. Fruit juice (esp. fresh juices), rich in the acid which speeds up the dissolution of antibiotics, not only reduces drug efficacy, but also produce adverse effects.